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ITGAV & Ad fiber knob
Loading...Anti-ITGAV & Ad fiber knob ProductsBackground
Anti-ITGAV & Ad fiber knob Products
- AbPlus™ Anti-ITGAV Magnetic Beads (13C2) (VS-0424-XY160)
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- Target: ITGAV
- Target Species: Human, African Green Monkey, Rabbit, Bovine
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
Background
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Ad fiber knob is expressed in adenovirus.