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KYNU

Anti-KYNU Products
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- Species Reactivity: Human
- Application: WB
- AbPlus™ Anti-KYNU Magnetic Beads (VS-0724-YC123) (VS-0724-YC123)
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- Target: KYNU
- Target Species: Human
- Application: IP, Protein Purification
- AbPlus™ Anti-Kynu Magnetic Beads (VS-0724-YC122) (VS-0724-YC122)
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- Target: Kynu
- Target Species: Mouse
- Application: IP, Protein Purification
- Anti-Rat KYNU Immunohistochemistry Kit (VS-0525-XY3905)
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- Species Reactivity: Human, Rat
- Target: KYNU
- Application: IHC
- Anti-Mouse KYNU Immunohistochemistry Kit (VS-0525-XY3904)
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- Species Reactivity: Mouse
- Target: KYNU
- Application: IHC
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- Species Reactivity: Mouse
- Type: IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.
Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (monocytes, Langerhans cells, Basal respiratory cells, Macrophages, Ionocytes, Club cells, Syncytiotrophoblasts)
Immune cell specificity
Group enriched (intermediate monocyte, non-classical monocyte, myeloid DC, classical monocyte, plasmacytoid DC, memory B-cell, naive B-cell)
Cell line specificity
Cell line enhanced
Interaction
Homodimer.
Molecular function
Hydrolase
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