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LGALS8

Anti-LGALS8 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
- Recombinant Mouse Anti-Human LGALS8 Antibody (MOB-1052MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
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- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ELISA
- Anti-LGALS8 Immunohistochemistry Kit (VS-0525-XY4004)
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- Species Reactivity: Human
- Target: LGALS8
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, IHC-P, ICC, FC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Early spermatids, Late spermatids, Syncytiotrophoblasts)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Low cell line specificity
Interaction
Homodimer (PubMed:21288902, Ref. 15). Interacts with CALCOCO2/NDP52 (PubMed:22246324). Interacts with PDPN; the interaction is glycosylation-dependent; may participate in connection of the lymphatic endothelium to the surrounding extracellular matrix.
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