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MAN1A1

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases.
Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Hepatocytes, Early spermatids, Excitatory neurons)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (ASC diff, Hep G2, Karpas-707, U-266/70)

Molecular function

Glycosidase, Hydrolase

More Types Infomation
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