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MFN1
Loading...Anti-MFN1 Products
- Mouse Anti-Mfn1 Recombinant Antibody (clone mN111/24R) (VS-0422-LC143)
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- Species Reactivity: Rat, Mouse
- Type: Mouse IgG2a
- Application: WB
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- Rat Anti-Mfn1 Recombinant Antibody (clone rtN111/24R) (VS-0422-LC144)
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- Species Reactivity: Rat, Mouse
- Type: Rat IgG2b
- Application: WB
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- Rabbit Anti-Mfn1 Recombinant Antibody (clone rN111/24R) (VS-0422-LC145)
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- Species Reactivity: Rat, Mouse
- Type: Rabbit IgG
- Application: WB
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- Recombinant Mouse Anti-Human MFN1 Antibody (MOB-1928MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, ICC/IF, IHC-P, WB
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP, FC
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- Anti-MFN1 Immunohistochemistry Kit (VS-0325-XY1343)
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- Species Reactivity: Human, Mouse, Rat
- Target: MFN1
- Application: IHC
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More Infomation
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting. [provided by RefSeq, Jul 2008]
Protein class
Plasma proteins, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Inhibitory neurons)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer, also in the absence of bound GTP (PubMed:27920125, PubMed:28114303). Forms higher oligomers in the presence of a transition state GTP analog (PubMed:28114303). Forms homomultimers and heteromultimers with MFN2 (By similarity). Oligomerization is essential for mitochondrion fusion (PubMed:27920125, PubMed:28114303). Component of a high molecular weight multiprotein complex (PubMed:12759376). Interacts with VAT1 (By similarity). Interacts with THG1L; THG1L probably functions as a guanyl-nucleotide exchange factor/GEF, activating MFN1.
Molecular function
Hydrolase
More Types Infomation