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MMP17

Anti-MMP17 Products
- Recombinant Mouse Anti-MMP17 Antibody (CBL146) (NEUT-1744CQ)
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- Species Reactivity: Human
- Type: IgG2
- Application: ELISA, Neut
- Recombinant Mouse Anti-MMP17 Antibody (CBL659) (NEUT-1745CQ)
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- Species Reactivity: Human
- Type: IgG2a
- Application: Neut
- Recombinant Mouse Anti-MMP17 Antibody (MM0638-12N24) (NEUT-1746CQ)
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- Species Reactivity: Human
- Type: IgG2
- Application: Neut, ELISA
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: IF, IHC, WB
- Human Anti-MMP17 Recombinant Antibody (HPAB-0565-YJ) (HPAB-0565-YJ)
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- Species Reactivity: Human
- Type: Human IgG
- Application: FC, Block
- Human Anti-MMP17 Recombinant Antibody; scFv Fragment (HPAB-0565-YJ-S(P)) (HPAB-0565-YJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: FC, Block
- Human Anti-MMP17 Recombinant Antibody; Fab Fragment (HPAB-0565-YJ-F(E)) (HPAB-0565-YJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: FC, Block
- Anti-MMP17 Immunohistochemistry Kit (VS-0525-XY4450)
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- Species Reactivity: Human
- Target: MMP17
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC-P, ICC/IF, IHC-FoFr
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For Research Use Only. Not For Clinical Use.
MMP17 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor.
Protein class
Enzymes
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Group enriched (Excitatory neurons, Melanocytes, Oligodendrocyte precursor cells, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (REH, SK-MEL-30, WM-115)
Molecular function
Hydrolase, Metalloprotease, Protease
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