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MSRB1
Anti-MSRB1 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Acts as a regulator of actin assembly by reducing methionine (R)-sulfoxide mediated by MICALs (MICAL1, MICAL2 or MICAL3) on actin, thereby promoting filament repolymerization. Plays a role in innate immunity by reducing oxidized actin, leading to actin repolymerization in macrophages (By similarity).
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Hepatocytes, monocytes)
Immune cell specificity
Group enriched (neutrophil, eosinophil)
Cell line specificity
Low cell line specificity
Molecular function
Oxidoreductase
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