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MT-SP1
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- Human Anti-MT-SP1 Antibody (clone S4), mRNA (PABL-660-mRNA)
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- Species Reactivity: Human
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- Human Anti-MT-SP1 Antibody (clone E2), mRNA (PABZ-090-mRNA)
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- Species Reactivity: Human
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- Recombinant Anti-MT-SP1 Antibody (MOB-679)
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- Derivation: Mouse
- Type: IgG
- Application: ELISA, WB, FC, FuncS
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- Recombinant Human Anti-MT-SP1 Antibody (MHH-679)
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- Derivation: Human
- Type: IgG
- Application: FC, IP, FuncS
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- Recombinant Human Anti-MT-SP1 Antibody Fab Fragment (MHH-679-F(E))
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- Derivation: Human
- Type: Fab
- Application: ELISA, IF, FuncS
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- Recombinant Human Anti-MT-SP1 Antibody scFv Fragment (MHH-679-S(P))
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- Derivation: Human
- Type: scFv
- Application: ELISA, IP, FuncS
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- Recombinant Anti-MT-SP1 Antibody Fab Fragment (MOB-679-F(E))
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- Derivation: Mouse
- Type: Fab
- Application: IF, FuncS
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- Recombinant Anti-MT-SP1 Antibody scFv Fragment (MOB-679-S(P))
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- Derivation: Mouse
- Type: scFv
- Application: ELISA, WB, IP, FuncS
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For Research Use Only. Not For Clinical Use.
Background
The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008]