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NID2
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane.
Protein class
Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Fibroblasts, Adipocytes, Smooth muscle cells, Microglial cells, Endothelial cells, Theca cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, BJ, BJ hTERT+, HHSteC, HSkMC)
Interaction
Interacts with LAMA2 (By similarity). Interacts with COL13A1. Interacts with EFEMP2 (By similarity).
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