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NLGN3

Anti-NLGN3 Products

Rat Anti-NLGN3 Recombinant Antibody (VS-0522-LC118) (VS-0522-LC118)
- Species Reactivity: Rat, Human, Mouse
- Type: Rat IgG2b
- Application: WB, IF, IHC
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Human Anti-NLGN3 Recombinant Antibody (VS-0522-LC119) (VS-0522-LC119)
- Species Reactivity: Rat, Human, Mouse
- Type: Human IgG1
- Application: WB, IF, IHC
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Rabbit Anti-NLGN3 Recombinant Antibody (VS-0522-LC120) (VS-0522-LC120)
- Species Reactivity: Rat, Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC
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Recombinant Mouse anti-Human NLGN3 Monoclonal antibody (EML1574) (MOB-0218CT)
- Species Reactivity: Human
- Application: WB
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Hi-Affi™ Recombinant Rabbit Anti-NLGN3 Monoclonal Antibody (SI435DS) (MOR-4345)
- Species Reactivity: Human
- Type: IgG
- Application: FC
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Anti-NLGN3 Immunohistochemistry Kit (VS-0525-XY4863)
- Species Reactivity: Human
- Target: NLGN3
- Application: IHC
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Anti-Mouse NLGN3 Immunohistochemistry Kit (VS-0525-XY4864)
- Species Reactivity: Human, Mouse, Rat
- Target: NLGN3
- Application: IHC
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For Research Use Only. Not For Clinical Use.

Background

NLGN3 (Neuroligin 3) is a Protein Coding gene. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Diseases associated with NLGN3 include Autism X-Linked 1 and Asperger Syndrome, X-Linked 1.

Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Oligodendrocyte precursor cells, Oligodendrocytes, Astrocytes, Peritubular cells, Inhibitory neurons)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, NTERA-2, SH-SY5Y)

Interaction

Interacts with NRXN1, NRXN2 and NRXN3. Interacts (via its C-terminus) with DLG4/PSD-95 (via PDZ domain 3) (By similarity). Homodimer, and heterodimer with NLGN1 and NLGN2 (By similarity).

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