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NUCB1
Loading...Anti-NUCB1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, ICC, IF, IHC
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- Anti-NUCB1 Immunohistochemistry Kit (VS-0525-XY5029)
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- Species Reactivity: Human
- Target: NUCB1
- Application: IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
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- Chicken Anti-NUCB1 Polyclonal IgY (BRD-0400MZ)
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- Species Reactivity: Human, Mouse, Rat
- Type: Chicken antibody
- Application: WB
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For Research Use Only. Not For Clinical Use.
Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis (By similarity).
Protein class
Plasma proteins
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Proximal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts (via GBA motif) with guanine nucleotide-binding protein G(i) alpha subunits GNAI1, GNAI2 and GNAI3 with higher affinity for GNAI1 and GNAI3 than for GNAI2. Preferentially interacts with inactive rather than active GNAI3. Interaction with GNAI3 is inhibited when NUCB1 binds calcium, probably due to a conformational change which renders the GBA motif inaccessible.
Molecular function
DNA-binding, Guanine-nucleotide releasing factor
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