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Nuclear dot
Loading...Anti-Nuclear dot Products
- Mouse Anti-Nuclear dot Recombinant Antibody (clone H301) (FAMAB-0104YC)
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- Species Reactivity: Mouse
- Type: Mouse IgM, κ
- Application: ELISA, IF
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- Mouse Anti-Nuclear dot Antibody (clone H301), mRNA (FAMAB-0104YC-mRNA)
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- Species Reactivity: Mouse
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- Mouse Anti-Nuclear dot Recombinant Antibody (clone H301); scFv Fragment (FAMAB-0104-YC-S(P))
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- Species Reactivity: Mouse
- Type: Mouse scFv
- Application: ELISA, IF
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- Mouse Anti-Nuclear dot Recombinant Antibody (clone H301); Fab Fragment (FAMAB-0104-YC-F(E))
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- Species Reactivity: Mouse
- Type: Mouse Fab
- Application: ELISA, IF
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For Research Use Only. Not For Clinical Use.
Background
Nuclear dots (also known as Nuclear bodies, nuclear domains, or PML bodies) are punctate structures found in the nuclei of certain cells. Nuclear bodies (NBs) were first seen as prominent interchromatin structures in the nuclei of malignant or hyperstimulated animal cells identified using anti-sp100 autoantibodies from primary biliary cirrhosis and subsequently the promyelocytic leukemia (PML) factor, but appear also to be elevated in many autoimmune and cancerous diseases. Nuclear dots are metabolically stable and resistant to nuclease digestion and salt extraction.