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P. falciparum EBA-175

Anti-P. falciparum EBA-175 Products

Recombinant Anti-P. falciparum EBA-175 Antibody (MOB-739)
- Derivation: Mouse
- Species Reactivity: P. falciparum
- Type: IgG
- Application: WB, Dot, FuncS
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Recombinant Human Anti-P. falciparum EBA-175 Antibody (MHH-739)
- Derivation: Human
- Species Reactivity: P. falciparum
- Type: IgG
- Application: WB, Neut, FuncS
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Recombinant Human Anti-P. falciparum EBA-175 Antibody Fab Fragment (MHH-739-F(E))
- Derivation: Human
- Species Reactivity: P. falciparum
- Type: Fab
- Application: ELISA, WB, FC, FuncS
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Recombinant Human Anti-P. falciparum EBA-175 Antibody scFv Fragment (MHH-739-S(P))
- Derivation: Human
- Species Reactivity: P. falciparum
- Type: scFv
- Application: FC, Neut, Funcs
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Recombinant Anti-P. falciparum EBA-175 Antibody Fab Fragment (MOB-739-F(E))
- Derivation: Mouse
- Species Reactivity: P. falciparum
- Type: Fab
- Application: Neut, WB, FuncS
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Recombinant Anti-P. falciparum EBA-175 Antibody scFv Fragment (MOB-739-S(P))
- Derivation: Mouse
- Species Reactivity: P. falciparum
- Type: scFv
- Application: FC, IP, FuncS
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For Research Use Only. Not For Clinical Use.

Background

The Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175) is a ligand for merozoite invasion into human erythrocytes that binds to glycophorin A in a sialic acid-dependent manner. P. falciparum strain W2mef depends on sialic acid for invasion of erythrocytes, whereas 3D7 is sialic acid-independent.