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PIGS
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More Infomation
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a protein that is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.
Protein class
Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins
Predicted location
Membrane
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Forms a complex with PIGK/GPI8, PIGT, PIGU and GAA1.
More Types Infomation
Related Signaling Pathways
p53 Signaling Pathway