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For Research Use Only. Not For Clinical Use.


Protein kinase Cδ (or PKC-δ) is an enzyme encoded by the PRKCD gene in humans.

Protein kinase C (PKC) is a family of serine and threonine-specific protein kinases that can be activated by the second messenger diacylglycerol. PKC family members can phosphorylate a variety of protein targets and are known to participate in a variety of cell signaling pathways. Members of the PKC family also act as the main receptor for phorbol ester, a tumor promoter. Each member of the PKC family has a specific expression profile and is believed to play a different role in the cell. The protein encoded by this gene is one of the members of the PKC family. Studies in humans and mice have shown that this kinase is involved in the regulation of B cell signaling and the growth, apoptosis, and differentiation of various cell types.
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