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PRPS2
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Peritubular cells, Leydig cells, Sertoli cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homodimer. The active form is probably a hexamer composed of 3 homodimers (By similarity).
Molecular function
Kinase, Transferase
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