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PSG9

Anti-PSG9 Products
- Recombinant Anti-Human PSG9 Antibody (MOB-2767z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, Neut, FuncS
- Recombinant Anti-Human PSG9 Antibody Fab Fragment (MOB-2767z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: FC, Neut, Funcs
- Recombinant Anti-Human PSG9 Antibody scFv Fragment (MOB-2767z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
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More Infomation
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms.
Protein class
Plasma proteins
Predicted location
Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enriched (Syncytiotrophoblasts)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (BJ, GAMG, HBF TERT88, SuSa, U-2197)
Interaction
Interacts with latency-associated peptide; leading to TGFB1 activation.
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