RABEP1

Antibody Magnetic Beads AbPlus Formats

Anti-RABEP1 Recombinant Antibody Products

AbPlus™ Anti-RABEP1 Magnetic Beads (VS-0724-YC187) (VS-0724-YC187)
- Target: RABEP1
- Target Species: Human
- Application: IP, Protein Purification
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Mouse Anti-RABEP1 Recombinant Antibody (clone 21B3) (MOB-3353z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, IHC, ELISA
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For Research Use Only. Not For Clinical Use.

RABEP1 (Rabaptin, RAB GTPase Binding Effector Protein 1) is a Protein Coding gene. Diseases associated with RABEP1 include Tuberous Sclerosis 2. Among its related pathways are Delta508-CFTR traffic/Sorting endosome formation in CF and Vesicle-mediated transport. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and growth factor activity. An important paralog of this gene is RABEP2.

Protein class

Cancer-related genes

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer when bound to RAB5A (PubMed:15378032). Heterodimer with RABGEF1 (PubMed:11452015, PubMed:9323142). The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding (PubMed:10698684, PubMed:8521472, PubMed:20098723, PubMed:12773381). Interacts with TSC2 (PubMed:9045618). Interacts with GGA1 (via GAE domain), GGA2 (via GAE domain) and GGA3 (via GAE domain) (PubMed:12505986, PubMed:14665628). Interacts with AP1G1 (via GAE domain) (PubMed:12505986, PubMed:12773381, PubMed:14665628). Interacts with AP1G2 (via GAE domain) (PubMed:12505986, PubMed:14665628). Interacts with ECPAS (PubMed:20682791). Interacts with KCNH1 (By similarity). Interacts with PKD1 (via C-terminal domain) and GGA1; the interactions recruit PKD1:PKD2 complex to GGA1 and ARL3 at trans-Golgi network (By similarity). Interacts with KCNH1 (By similarity).

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