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S100A2
Loading...Anti-S100A2 Products
- Mouse Anti-S100A2 Recombinant Antibody (VS3-FY2868) (VS3-FY2868)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IHC, ICC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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- Rabbit Anti-S100A2 Recombinant Antibody (VS13-YC1027) (VS13-YC1027)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
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- Anti-S100A2 Immunohistochemistry Kit (VS-0325-XY1991)
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- Species Reactivity: Human, Mouse, Rat
- Target: S100A2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
Protein class
Cancer-related genes
Predicted location
Intracellular
Single cell type specificity
Group enriched (Basal keratinocytes, Basal respiratory cells, Prostatic glandular cells, Squamous epithelial cells, Urothelial cells, Basal prostatic cells, Basal squamous epithelial cells, Suprabasal keratinocytes, Club cells)
Immune cell specificity
Immune cell enhanced (basophil)
Cell line specificity
Group enriched (HBEC3-KT, RT4)
Interaction
Homodimer. Interacts with FKBP4. Interacts with PPP5C (via TPR repeats); the interaction is calcium-dependent and modulates PPP5C activity. Interacts with TPPP; this interaction inhibits TPPP dimerization (PubMed:33831707).
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