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SART3
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- PE-H-2Kd/Human SART3 (AYIDFEMKI) MHC Tetramer (MHC-CN1197)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: AYIDFEMKI
- Conjugate: PE
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- APC-H-2Kd/Human SART3 (AYIDFEMKI) MHC Tetramer (MHC-CN1198)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: AYIDFEMKI
- Conjugate: APC
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- FITC-H-2Kd/Human SART3 (AYIDFEMKI) MHC Tetramer (MHC-CN1199)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: AYIDFEMKI
- Conjugate: FITC
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- H-2Kd/Human SART3 (AYIDFEMKI) MHC Tetramer (MHC-CN1200)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: AYIDFEMKI
- Conjugate: Unconjugated
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- PE-A*02:01/Human SART3 (RLAEYQAYI) MHC Tetramer (MHC-CN1201)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: RLAEYQAYI
- Conjugate: PE
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- APC-A*02:01/Human SART3 (RLAEYQAYI) MHC Tetramer (MHC-CN1202)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: RLAEYQAYI
- Conjugate: APC
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- FITC-A*02:01/Human SART3 (RLAEYQAYI) MHC Tetramer (MHC-CN1203)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: RLAEYQAYI
- Conjugate: FITC
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- A*02:01/Human SART3 (RLAEYQAYI) MHC Tetramer (MHC-CN1204)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: RLAEYQAYI
- Conjugate: Unconjugated
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- A*02:01/Human SART3 (RLAEYQAYI) MHC Pentamer (MHC-YF711)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: RLAEYQAYI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- H-2Kd/Human SART3 (AYIDFEMKI) MHC Pentamer (MHC-YF712)
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- Class: Class I
- Antigen: SART3
- Antigen Species: Human
- Peptide: AYIDFEMKI
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Anti-SART3 Immunohistochemistry Kit (VS-0325-XY2006)
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- Species Reactivity: Human, Mouse, Rat
- Target: SART3
- Application: IHC
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
Protein class
Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the 7SK snRNP complex at least composed of P-TEFb (composed of CDK9 and CCNT1/cyclin-T1), HEXIM1, HEXIM2, BCDIN3, SART3 proteins and 7SK and U6 snRNAs (PubMed:17643375). Interacts with AGO1 and AGO2 (PubMed:17932509). Interacts with PRPF3 and USP4; the interaction with PRPF3 is direct and recruits USP4 to its substrate PRPF3 (PubMed:15314151, PubMed:20595234). Interacts with USP15; the interaction is direct (PubMed:24526689). Interacts with HIV-1 Tat (PubMed:11959860).
Molecular function
RNA-binding
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