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SESTD1

Anti-SESTD1 Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IP, FuncS
- Mouse Anti-NHP SESTD1 Recombinant Antibody (clone OTI7G4) (VS-1024-XY473)
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- Species Reactivity: Dog, Human, Mouse, Non-human primate
- Type: Mouse IgG2b
- Application: WB, IHC, ICC
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- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IHC-P
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For Research Use Only. Not For Clinical Use.
Background
Enables phosphatidylinositol-3,4-bisphosphate binding activity and phospholipid binding activity. Involved in negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel. Located in intermediate filament cytoskeleton. Colocalizes with calcium channel complex.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Oligodendrocytes, Horizontal cells, Glandular and luminal cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (ASC diff)
Interaction
Interacts (via the spectrin 1 repeat) with TRPC4 and TRPC5 (via CIRB domain). Interacts with CTNNB1.
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