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SIGLEC7 / SIGLEC9 / SIGLEC12

Anti-SIGLEC7 / SIGLEC9 / SIGLEC12 Products
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt, Neut
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, Cyt, Neut
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Cyt, Neut
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, Cyt, Neut
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Cyt, Neut
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, Cyt, Neut
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For Research Use Only. Not For Clinical Use.
Background
Sialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to theimmunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to differentsialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like.