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SIX4
Anti-SIX4 Recombinant Antibody Products
- Anti-SIX4 Immunohistochemistry Kit (VS-0325-XY2075)
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- Species Reactivity: Human, Mouse
- Target: SIX4
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010]
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Glandular and luminal cells, Endometrial ciliated cells, Respiratory ciliated cells, Prostatic glandular cells, Cone photoreceptor cells, Urothelial cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (A-431, hTERT-RPE1, RH-30)
Interaction
Interacts with EYA3; acts cooperatively with EYA3 to transactivate target genes through interaction and nuclear translocation of EYA3 protein.
Molecular function
Developmental protein, DNA-binding
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