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SLC18A1

Anti-SLC18A1 Products

Recombinant Mouse anti-Human SLC18A1 Monoclonal antibody (EML2237) (MOB-2224CT)
- Species Reactivity: Human
- Application: WB
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Hi-Affi™ Recombinant Rabbit Anti-SLC18A1 Monoclonal Antibody (DS3286AB) (MOR-3286)
- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.

Background

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles, using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine. See also SLC18A2 (MIM 193001).

Protein class

FDA approved drug targets, Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Enteroendocrine cells)

Immune cell specificity

Immune cell enhanced (non-classical monocyte)

Cell line specificity

Cell line enriched (SH-SY5Y)

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