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SRD5A2
Loading...Anti-SRD5A2 Products
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
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- Rabbit Anti-SRD5A2 Recombinant Antibody (VS13-YC1111) (VS13-YC1111)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IP
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- Anti-SRD5A2 Immunohistochemistry Kit (VS-0525-XY6893)
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- Species Reactivity: Human
- Target: SRD5A2
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
Protein class
Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Early spermatids, Late spermatids, Endometrial ciliated cells, Hepatocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (RT4)
Molecular function
Oxidoreductase
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