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SRD5A2

Anti-SRD5A2 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a microsomal protein expressed at high levels in androgen-sensitive tissues such as the prostate. The encoded protein is active at acidic pH and is sensitive to the 4-azasteroid inhibitor finasteride. Deficiencies in this gene can result in male pseudohermaphroditism, specifically pseudovaginal perineoscrotal hypospadias (PPSH).
Protein class

Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Transporters

Predicted location

Membrane

Single cell type specificity

Group enriched (Early spermatids, Late spermatids, Endometrial ciliated cells, Hepatocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (RT4)

Molecular function

Oxidoreductase

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