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SRI

Anti-SRI Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene. [provided by RefSeq, Mar 2012]
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Paneth cells, Extravillous trophoblasts, Proximal enterocytes, Distal enterocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Homodimer. Interacts with GCA, RYR2 and ANXA7.

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