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SSH3
Anti-SSH3 Recombinant Antibody Products
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For Research Use Only. Not For Clinical Use.
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008]
Protein class
Enzymes, Metabolic proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Immune cell enhanced (basophil, eosinophil)
Cell line specificity
Cell line enhanced (HaCaT, MCF7, RT4)
Interaction
Does not bind to, or colocalize with, filamentous actin.
Molecular function
Hydrolase, Protein phosphatase
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