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SYT11
Anti-SYT11 Recombinant Antibody Products
- AbPlus™ Anti-SYT11 Magnetic Beads (VS-0724-YC935) (VS-0724-YC935)
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- Target: SYT11
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is also a substrate for ubiquitin-E3-ligase parkin.
Predicted location
Intracellular
Single cell type specificity
Group enriched (Muller glia cells, Oligodendrocytes, Oligodendrocyte precursor cells, Inhibitory neurons, Astrocytes, Horizontal cells, Excitatory neurons, Bipolar cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (Karpas-707, SCLC-21H, SH-SY5Y, U-87 MG)
Interaction
Homodimer. Can also form heterodimers. Interacts with PRKN (PubMed:12925569). Interacts (via C2 2 domain) with AGO2 and SND1; the interaction with SND1 is direct. Interacts with KIF1A; the interaction increases in presence of calcium (By similarity).
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