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Tax

Anti-Tax Products
- Human Anti-Tax Recombinant Soluble TCR (clone A33) (scTCR-1121YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGFAVYV + SCM(F5)
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A34) (scTCR-1122YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGFPVFV + SCM(F5)
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A35) (scTCR-1123YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGFPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A36) (scTCR-1124YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGFPVYV + SCM(F5)
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A37) (scTCR-1125YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGKPVYV + SCM(K5)
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A38) (scTCR-1126YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYAVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (J.O.4) (KIH) (VS-0622-YF7850)
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- Epitope: LLFGYPVYV
- MHC: HLA-A2
- Recombinant Human Anti-Tax Soluble TCR (VC3) (KIH) (VS-0622-YF7851)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AF5) (KIH) (VS-0622-YF7843)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AG9) (KIH) (VS-0622-YF7844)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AH6) (KIH) (VS-0622-YF7845)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (KIH) (VS-0622-YF7846) (VS-0622-YF7846)
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- Species Reactivity: HIV1
- Epitope: LLFGFPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (BB4) (KIH) (VS-0622-YF7848)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (BB6) (KIH) (VS-0622-YF7849)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c1) (KIH) (VS-0622-YF7837)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c111) (KIH) (VS-0622-YF7838)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c2) (KIH) (VS-0622-YF7839)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c89) (KIH) (VS-0622-YF7840)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6-X15) (KIH) (VS-0622-YF7841)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AE10) (KIH) (VS-0622-YF7842)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (C-Cys) (VS-0622-YF5138) (VS-0622-YF5138)
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- Species Reactivity: HIV1
- Epitope: LLFGFPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (BB4) (C-Cys) (VS-0622-YF5140)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (BB6) (C-Cys) (VS-0622-YF5141)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (J.O.4) (C-Cys) (VS-0622-YF5142)
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- Epitope: LLFGYPVYV
- MHC: HLA-A2
- Recombinant Human Anti-Tax Soluble TCR (VC3) (C-Cys) (VS-0622-YF5143)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (KIH) (VS-0622-YF7826) (VS-0622-YF7826)
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- Species Reactivity: HTLV1
- Epitope: LLFGFAVYV + SCM(F5)
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c89) (C-Cys) (VS-0622-YF5132)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6-X15) (C-Cys) (VS-0622-YF5133)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AE10) (C-Cys) (VS-0622-YF5134)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AF5) (C-Cys) (VS-0622-YF5135)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AG9) (C-Cys) (VS-0622-YF5136)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AH6) (C-Cys) (VS-0622-YF5137)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (J.O.4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2434)
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- Epitope: LLFGYPVYV
- MHC: HLA-A2
- Recombinant Human Anti-Tax Soluble TCR (VC3) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2435)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (C-Cys) (VS-0622-YF5118) (VS-0622-YF5118)
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- Species Reactivity: HTLV1
- Epitope: LLFGFAVYV + SCM(F5)
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c1) (C-Cys) (VS-0622-YF5129)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c111) (C-Cys) (VS-0622-YF5130)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c2) (C-Cys) (VS-0622-YF5131)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AF5) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2427)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AG9) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2428)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AH6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2429)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
-
- Species Reactivity: HIV1
- Epitope: LLFGFPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (BB4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2432)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (BB6) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2433)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2421)
-
- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c111) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2422)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c2) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2423)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6c89) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2424)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (A6-X15) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2425)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Recombinant Human Anti-Tax Soluble TCR (AE10) (ZIP-Fos/ZIP-Jun) (VS-0622-YF2426)
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone J.O.4) (scTCR-1145YC-S(P))
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- Epitope: LLFGYPVYV
- MHC: HLA-A2
- Human Anti-Tax Recombinant Soluble TCR (clone VC3) (scTCR-1146YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- A*02:01/HTLV Tax (LLFGYPVYV) MHC Monomer (MHC-YF226)
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- Class: Class I
- Antigen: Tax
- Antigen Species: HTLV
- Peptide: LLFGYPVYV
- Conjugate: Biotin
- A*0201/HTLV Tax (LLFGYPVYV) MHC Monomer (MHC-YF268)
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- Class: Class I
- Antigen: Tax
- Antigen Species: HTLV
- Peptide: LLFGYPVYV
- Conjugate: Biotin
- A*24:02/HTLV Tax (SFHSLHLLF) MHC Pentamer (MHC-YF735)
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- Class: Class I
- Antigen: Tax
- Antigen Species: HTLV
- Peptide: SFHSLHLLF
- Conjugate: Unlabeled, Biotin, R-PE, APC
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- Species Reactivity: HTLV1
- Epitope: LLFGFAVYV + SCM(F5)
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone AG9) (scTCR-1139YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone AH6) (scTCR-1140YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone (B7)-1) (scTCR-1141YC-S(P))
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- Species Reactivity: HIV1
- Epitope: LLFGFPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone (B7)-2) (scTCR-1142YC-S(P))
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- Species Reactivity: HIV1
- Epitope: LLFGFPVYV + SCM(F5)
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone BB4) (scTCR-1143YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone BB6) (scTCR-1144YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A6c111) (scTCR-1133YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A6c2) (scTCR-1134YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A6c89) (scTCR-1135YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A6-X15) (scTCR-1136YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone AE10) (scTCR-1137YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone AF5) (scTCR-1138YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A39) (scTCR-1127YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPRYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A40) (scTCR-1128YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVAV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A41) (scTCR-1129YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVFV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A42) (scTCR-1130YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLYGFVNYI
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A43) (scTCR-1131YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLYGFVNYV
- MHC: HLA-A*02:01
- Human Anti-Tax Recombinant Soluble TCR (clone A6c1) (scTCR-1132YC-S(P))
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- Species Reactivity: HTLV1
- Epitope: LLFGYPVYV
- MHC: HLA-A*02:01
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For Research Use Only. Not For Clinical Use.
Background
Transcriptional activator that governs the viral transcription from the 5'LTR via the recruitment of dimers of host phosphorylated CREB1. Together they bind cAMP response elements within the viral promoter and mediate high-level viral transcription. Increases host CREB1 O-GlcNAcylation to further increase 5'LTR transactivation. Modulates also the expression of cellular genes leading to the deregulation of T-cell proliferation, perturbing the integrity of cell cycle checkpoints, the DNA damage response and apopototic pathways. Acts as an ubiquitin E3 ligase and stimulates host IKK complex by catalyzing the assembly of free mixed-linkage polyubiquitin chains, resulting in constitutive activation of the transcription factor NF-kappa-B. Inhibits the host nonsense-mediated mRNA decay (NMD), a cellular process that can actively degrade mRNAs by interacting with host UPF1.