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TcdA and TcdB
Loading...Anti-TcdA and TcdB Products
- Mouse Anti-TcdA and TcdB Recombinant Antibody (HPAB-AP193-YC) (HPAB-AP193-YC)
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- Species Reactivity: C. difficile
- Type: Mouse IgG
- Application: WB, Neut
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- Mouse Anti-TcdA and TcdB Recombinant Antibody (HPAB-AP194-YC) (HPAB-AP194-YC)
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- Species Reactivity: C. difficile
- Type: Mouse IgG
- Application: WB, Neut
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- Mouse Anti-TcdA and TcdB Recombinant Antibody (HPAB-AP195-YC) (HPAB-AP195-YC)
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- Species Reactivity: C. difficile
- Type: Mouse IgG
- Application: WB, Neut
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- Human Anti-TcdA and TcdB Recombinant Antibody (HPAB-AP196-YC) (HPAB-AP196-YC)
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- Species Reactivity: C. difficile
- Type: Human IgG
- Application: WB, Neut
Compare
- Human Anti-TcdA and TcdB Recombinant Antibody (HPAB-AP197-YC) (HPAB-AP197-YC)
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- Species Reactivity: C. difficile
- Type: Human IgG
- Application: WB, Neut
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- Mouse Anti-TcdA and TcdB Recombinant Antibody; scFv Fragment (HPAB-AP193-YC-S(P)) (HPAB-AP193-YC-S(P))
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- Species Reactivity: C. difficile
- Type: Mouse scFv
- Application: WB, Neut
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- Mouse Anti-TcdA and TcdB Recombinant Antibody; Fab Fragment (HPAB-AP195-YC-F(E)) (HPAB-AP195-YC-F(E))
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- Species Reactivity: C. difficile
- Type: Mouse Fab
- Application: WB, Neut
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- Human Anti-TcdA and TcdB Recombinant Antibody; Fab Fragment (HPAB-AP196-YC-F(E)) (HPAB-AP196-YC-F(E))
-
- Species Reactivity: C. difficile
- Type: Human Fab
- Application: WB, Neut
Compare
- Human Anti-TcdA and TcdB Recombinant Antibody; Fab Fragment (HPAB-AP197-YC-F(E)) (HPAB-AP197-YC-F(E))
-
- Species Reactivity: C. difficile
- Type: Human Fab
- Application: WB, Neut
Compare
- Mouse Anti-TcdA and TcdB Recombinant Antibody; scFv Fragment (HPAB-AP194-YC-S(P)) (HPAB-AP194-YC-S(P))
-
- Species Reactivity: C. difficile
- Type: Mouse scFv
- Application: WB, Neut
Compare
- Mouse Anti-TcdA and TcdB Recombinant Antibody; scFv Fragment (HPAB-AP195-YC-S(P)) (HPAB-AP195-YC-S(P))
-
- Species Reactivity: C. difficile
- Type: Mouse scFv
- Application: WB, Neut
Compare
- Human Anti-TcdA and TcdB Recombinant Antibody; scFv Fragment (HPAB-AP196-YC-S(P)) (HPAB-AP196-YC-S(P))
-
- Species Reactivity: C. difficile
- Type: Human scFv
- Application: WB, Neut
Compare
- Human Anti-TcdA and TcdB Recombinant Antibody; scFv Fragment (HPAB-AP197-YC-S(P)) (HPAB-AP197-YC-S(P))
-
- Species Reactivity: C. difficile
- Type: Human scFv
- Application: WB, Neut
Compare
- Mouse Anti-TcdA and TcdB Recombinant Antibody; Fab Fragment (HPAB-AP193-YC-F(E)) (HPAB-AP193-YC-F(E))
-
- Species Reactivity: C. difficile
- Type: Mouse Fab
- Application: WB, Neut
Compare
- Mouse Anti-TcdA and TcdB Recombinant Antibody; Fab Fragment (HPAB-AP194-YC-F(E)) (HPAB-AP194-YC-F(E))
-
- Species Reactivity: C. difficile
- Type: Mouse Fab
- Application: WB, Neut
Compare
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For Research Use Only. Not For Clinical Use.
Background
Toxin A and toxin B are both members of the large clostridial glucosylating toxin family, which also includes lethal toxin (TcsL) and hemorrhagic toxin (TcsH) from Clostridium sordellii, alpha toxin (TcnA) from Clostridium novyi and TpeL from Clostridium perfringens. The toxins are very large, being between 250 and 308 kDa in size, and have a high degree of sequence identity. Both toxin A and toxin B are proinflammatory and cytotoxic, causing disruption of the actin cytoskeleton and impairment of tight junctions in human intestinal epithelial cells, with resulting fluid accumulation and extensive damage to the large intestine.