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Toxin A

Anti-Toxin A Products

Human Anti-Toxin A Recombinant Antibody (HPAB-0593-YJ) (HPAB-0593-YJ)
- Derivation: Humanized
- Species Reactivity: C. difficile
- Type: Humanized IgG1, κ
- Application: ELISA, Neut, WB, FuncS
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Human Anti-Toxin A Recombinant Antibody; scFv Fragment (HPAB-0593-YJ-S(P)) (HPAB-0593-YJ-S(P))
- Derivation: Humanized
- Species Reactivity: C. difficile
- Type: Humanized scFv
- Application: ELISA, Neut, WB, FuncS
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Human Anti-Toxin A Recombinant Antibody; Fab Fragment (HPAB-0593-YJ-F(E)) (HPAB-0593-YJ-F(E))
- Derivation: Humanized
- Species Reactivity: C. difficile
- Type: Humanized Fab
- Application: ELISA, Neut, WB, FuncS
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For Research Use Only. Not For Clinical Use.

Background

C. difficile (or C. diff) is a Gram-positive, spore-forming, anaerobic bacterium that represents the leading cause of nosocomial (hospital-acquired) antibiotic-associated diarrhea and pseudomembranous colitis. Clostridium difficile toxin A (TcdA) is a toxin generated by Clostridium difficile. It is similar to Clostridium difficile Toxin B. The toxins are the main virulence factors produced by the gram positive, anaerobic, Clostridium difficile bacteria. The toxins function by damaging the intestinal mucosa and cause the symptoms of C. difficile infection, including pseudomembranous colitis.