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UBE2F

Anti-UBE2F Products
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF
- Anti-UBE2F Immunohistochemistry Kit (VS-0525-XY7697)
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- Species Reactivity: Human
- Target: UBE2F
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.