Membrane
Cell type enhanced (Alveolar cells type 1, Breast myoepithelial cells, Squamous epithelial cells, Respiratory ciliated cells, Alveolar cells type 2)
Not detected in immune cells
Cell line enhanced (fHDF/TERT166, HAP1, HDLM-2, HHSteC, JURKAT)
Interacts with KLRK1/NKG2D (PubMed:11777960). Does not bind to beta2-microglobulin (PubMed:12782710). (Microbial infection) In CMV-infected cells, interacts with the viral glycoprotein UL16; this interaction causes ULBP1 retention in the endoplasmic reticulum and cis-Golgi and prevents binding to and activation of KLRK1/NKG2D, providing CMV with an immune evasion mechanism.
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.