


ULBP1

Anti-ULBP1 Products
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: FC, Neut
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: Neut, FC
- Mouse Anti-ULBP1 Recombinant Antibody (clone CBL195) (NEUT-2241CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2
- Application: FC, Neut
- Mouse Anti-ULBP1 Recombinant Antibody (clone CBL342) (NEUT-2242CQ)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: Block, CyTOF, FC
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA, WB
- Mouse Anti-ULBP1 Recombinant Antibody (clone 3A6F11) (VS7-0425-WR1092)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC
- Mouse Anti-ULBP1 Recombinant Antibody (clone 7A5A3) (VS7-0425-WR1093)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
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For Research Use Only. Not For Clinical Use.
Background
Membrane
Cell type enhanced (Alveolar cells type 1, Breast myoepithelial cells, Squamous epithelial cells, Respiratory ciliated cells, Alveolar cells type 2)
Not detected in immune cells
Cell line enhanced (fHDF/TERT166, HAP1, HDLM-2, HHSteC, JURKAT)
Interacts with KLRK1/NKG2D (PubMed:11777960). Does not bind to beta2-microglobulin (PubMed:12782710). (Microbial infection) In CMV-infected cells, interacts with the viral glycoprotein UL16; this interaction causes ULBP1 retention in the endoplasmic reticulum and cis-Golgi and prevents binding to and activation of KLRK1/NKG2D, providing CMV with an immune evasion mechanism.