VACWR150

VACWR150, also known as Protein A27, is encoded by the gene A27L and is about 14 kDa in size. VACWR150 is an essential protein in the formation of intracellular enveloping viruses. In addition, relevant studies have found that VACWR150 protein also plays an important role in the assembly process of VV(vaccinia virus). When cells are infected by VV, the expression of A27L is seriously inhibited, which results in the inhibition of the transport process of mature viruses(IMV) in cells.There is a certain correlation between the transport anomalies of the mature virus in the cell and the morphology of the virus.All in all, VACWR150 involved in the envelopment of mature virion (MV) to form the wrapped virion (WV) and Participated in mature virion (MV) movement within the infected cell.