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VTI1B
Anti-VTI1B Recombinant Antibody Products
- AbPlus™ Anti-VTI1B Magnetic Beads (VS-0724-YC1088) (VS-0724-YC1088)
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- Target: VTI1B
- Target Species: Human
- Application: IP, Protein Purification
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- Recombinant Anti-Human VTI1B Antibody Fab Fragment (MOB-2862z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, Neut, FuncS
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- Recombinant Anti-Human VTI1B Antibody scFv Fragment (MOB-2862z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IP, FuncS
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For Research Use Only. Not For Clinical Use.
VTI1B (Vesicle Transport Through Interaction With T-SNAREs 1B) is a Protein Coding gene. Diseases associated with VTI1B include Hypomyelinating Leukodystrophy. Among its related pathways are wtCFTR and deltaF508 traffic/Late endosome and Lysosome (norm and CF) and Response to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene include SNARE binding and chloride channel inhibitor activity. An important paralog of this gene is VTI1A.
Protein class
Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Component of the SNARE complex composed of STX7, STX8, VAMP7 and VIT1B that is required for heterotypic fusion of late endosomes with lysosomes (By similarity). May interact with STX17 (PubMed:23217709). Interacts with CLINT1 (PubMed:18033301).
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