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VZV gpIII

Anti-VZV gpIII Products
- Recombinant Mouse Anti-VZV gpIII Antibody (SG3) (MRO-1356CQ)
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- Derivation: Mouse
- Species Reactivity: VZV
- Type: Mouse antibody
- Application: IF, IP, WB
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For Research Use Only. Not For Clinical Use.
Varicella zoster virus (VZV) is one of eight herpesviruses known to infect humans. VZV infections are species-specific to humans. It causes chickenpox (varicella), a disease most commonly affecting children, teens and young adults and herpes zoster (shingles) in older adults; shingles is rare in children. VZV is known by many names, including chickenpox virus, varicella virus, zoster virus, and human herpesvirus type 3 (HHV-3). VZV gB, based on homology with HSV gB, is likely critical for entry of virus into cells. gE is binds to a cellular receptor (insulin degrading enzyme and gH and gM are important for cell-to-cell spread of virus. gI facilitates maturation of gE ,and gL is a chaperone for gH. gK may be important for syncytia formation.