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Valproic Acid

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Anti-Valproic Acid Products

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For Research Use Only. Not For Clinical Use.


Valproic acid is primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches. It has recently been shown to protect against a seizure-induced reduction in phosphatidylinositol (3,4,5)-trisphosphate (PIP3) as a potential therapeutic mechanism. In addition, its anticonvulsant effect has been attributed to the blockade of voltage-dependent sodium channels and increased brain levels of gamma-aminobutyric acid (GABA). Valproic acid was first made in 1881 and came into medical use in 1962. It is on the World Health Organization's List of Essential Medicines.
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