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ZGPAT

ZGPAT

Engineered Antibody

Transcription repressor that specifically binds the 5-GGAG[GA]A[GA]A-3 consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis.

Human Anti-ZGPAT Recombinant Antibody (clone D298) (DrMAB-698)
- Species Reactivity: Human
- Type: Human IgG
- Application: IP, IF, ELISA, IP-MS

Human Anti-ZGPAT Recombinant Antibody (clone D296); Fab Fragment (DrMAB-696)
- Species Reactivity: Human
- Type: Human Fab
- Application: IP, IF, ELISA, IP-MS

Human Anti-ZGPAT Recombinant Antibody (ZG-432C) (ZG-432C)
- Species Reactivity: Human
- Type: Human IgG1, κ
- Application: ELISA, IP

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For Research Use Only. Not For Clinical Use.

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