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acrB
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- Mouse Anti-acrB Recombinant Antibody (clone 2506W0213) (VS-0625-FY318)
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- Species Reactivity: Escherichia coli (strain K12)
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
AcrB is a prominent inner membrane component of the AcrAB-TolC tripartite efflux pump system in Gram-negative bacteria. This pump actively expels a wide range of structurally diverse antibiotics, dyes, and other toxic compounds from the bacterial cell. AcrB's role is crucial in conferring multidrug resistance by utilizing proton motive force to efflux substrates, contributing significantly to antibiotic resistance.