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For Research Use Only. Not For Clinical Use.


D-alanine-D-alanine ligase A (DdlA) is a specific isoform of D-alanine-D-alanine ligase in bacteria. Like other Ddl enzymes, it synthesizes D-alanyl-D-alanine, a vital precursor for bacterial cell wall peptidoglycan. DdlA is an important target for existing antibiotics, and understanding its variants helps in combating resistance.
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