icd

icd, or Isocitrate dehydrogenase [NADP], is a key enzyme in the citric acid cycle. It catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate, producing NADPH. In bacteria, icd often serves a dual role, also contributing to anaplerotic reactions by providing α-ketoglutarate for amino acid synthesis, making it crucial for metabolism.