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lfrR
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- Mouse Anti-lfrR Recombinant Antibody (clone 2506W0533) (VS-0625-FY638)
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- Species Reactivity: Mycobacterium smegmatis
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.
lfrR, or TetR family transcriptional regulator, is a repressor protein that controls the expression of genes involved in multidrug resistance in Mycobacterium smegmatis. LfrR binds to the promoter regions of efflux pump genes, repressing their expression. Its inactivation leads to increased drug efflux and resistance, particularly to fluoroquinolones.