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For Research Use Only. Not For Clinical Use.


pgl, or 6-phosphogluconolactonase, is an enzyme in the pentose phosphate pathway (PPP). It catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. This is an early step in the PPP, which generates NADPH (for reductive biosynthesis and antioxidant defense) and precursors for nucleotide synthesis.
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