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speB

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For Research Use Only. Not For Clinical Use.


Background

speB, or Streptopain, also known as streptococcal pyrogenic exotoxin B (SPE B), is a potent cysteine protease produced by Streptococcus pyogenes. SpeB is a major virulence factor that degrades host proteins, including immunoglobulins and extracellular matrix components, contributing to tissue destruction and evasion of the immune system in streptococcal infections.
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