APC-H-2Kd/NRP-V7 (KYNKANVFL) MHC Tetramer
CAT#: MHC-LC697
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of NRP-V7-derived peptide of KYNKANVFL sequence and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specifications
- Allele
- H-2Kd
- Class
- Class I
- MHC Species
- Mouse
- Antigen
- NRP-V7
- Peptide
- KYNKANVFL
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- NRP-V7 is a H-2Kd-restricted epitope that is recognized by T-cell receptors expressed by CD8 cells.
- Alternative Names
- NRP-V7
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Consistent and Reliable Across Studies
Its robust and reproducible performance ensures dependable results, which is crucial for longitudinal studies monitoring T cell behavior over time, providing essential data for research progression.
Reliable Tool for T Cell Research
Its precise application in identifying antigen-specific T cells ensures accurate data generation, underpinning studies into immune recognition, response, and potential therapeutic interventions in immunology.
Q&As
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What is the primary use of the APC-H-2Kd/NRP-V7 MHC Tetramer?
A: This MHC tetramer is used in flow cytometry to identify and analyze CD8+ T cells specific for the NRP-V7 peptide. It is particularly valuable in cancer immunology and autoimmunity research for understanding T cell responses.
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How does specificity impact the reliability of this tetramer's applications?
A: The tetramer's high specificity ensures that only T cells reactive to the NRP-V7 peptide are detected, providing accurate data critical for studying immune responses in cancer or autoimmune disease research.
View the frequently asked questions answered by Creative Biolabs Support.
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See other products for "NRP-V7"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC696 | PE-H-2Kd/NRP-V7 (KYNKANVFL) MHC Tetramer | FCM | |
| MHC-YF147 | H-2Kd/ NRP-V7 (KYNKANVFL) MHC Monomer | MHC Multimer |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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