PE-H-2Kd/NRP-V7 (KYNKANVFL) MHC Tetramer

CAT#: MHC-LC696

This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of NRP-V7-derived peptide of KYNKANVFL sequence and H-2Kd molecule. The pMHC tetramer recognizes mouse CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.

Specifications

  • Allele
  • H-2Kd
  • Class
  • Class I
  • MHC Species
  • Mouse
  • Antigen
  • NRP-V7
  • Peptide
  • KYNKANVFL
  • Conjugate
  • PE
  • Application
  • FCM

Target

  • Antigen Introduction
  • NRP-V7 is a H-2Kd-restricted epitope that is recognized by T-cell receptors expressed by CD8 cells.
  • Alternative Names
  • NRP-V7
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Breast cancer biomarkers at key points during disease progression
Excellent for Immuno Research
The NRP-V7 Tetramer has been pivotal in our lab's studies of T-cell responses. Its specific recognition allows precise identification, helping us better understand immune dynamics in our experimental mouse models. We've found it provides clear, distinct data in flow cytometry analyses, which is invaluable for our cancer immunology projects.
Breast cancer biomarkers at key points during disease progression
Superb Quality Performance
The high-grade quality of the PE conjugate provides excellent fluorescence, crucial for the accuracy needed in flow cytometry. Our lab has repeated many tests, all resulting in a robust performance of the tetramer, validating our immunological assays effectively.
Breast cancer biomarkers at key points during disease progression
High-Precision Flow Cytometry
The incorporation of this tetramer into our flow cytometry assays has never been smoother. PE conjugation provides reliable fluorescence without fuss, minimizing noise and maximizing data reliability in immune surveillance studies.

Q&As

  1. What is the primary application of the PE-H-2Kd/NRP-V7 MHC Tetramer?

    A: The primary application of PE-H-2Kd/NRP-V7 MHC Tetramer is in flow cytometry (FCM) for analyzing antigen-specific CD8 T cells. This allows researchers to identify and study specific immune cell populations in various experimental settings.

  2. Can this MHC Tetramer be used in cancer immunology research?

    A: Yes, it is particularly useful in cancer immunology research where the immune response needs to be characterized, especially in studying the role of T-cells in tumor recognition and elimination.

  3. Does the tetramer carry any conjugate for detection?

    A: Yes, the tetramer is conjugated with phycoerythrin (PE), which fluoresces under the laser in a flow cytometer, aiding in the detection of specific T-cells.

View the frequently asked questions answered by Creative Biolabs Support.

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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