Recombinant Mouse Anti-Aspartic protease Bla g 2 Antibody (7C11) (CAT#: PABL-016)
Recombinant Mouse Antibody (7C11) is capable of binding to Aspartic protease Bla g 2, expressed in Chinese Hamster Ovary cells (CHO).
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ELISA
Figure 1 Dose-response curves of Bla g 2 and epitope mutants by ELISA.
Binding of the anti-Bla g 2 polyclonal antibody to mAb 7C11 epitope mutants.
Glesner, J., Wünschmann, S., Li, M., Gustchina, A., Wlodawer, A., Himly, M., ... & Pomés, A. (2011). Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding. PloS one, 6(7).
Inhib
Figure 2 Inhibition of biotinylated mAb binding to rBla g 2 by allergen mutants using ELISA.
Inhibition of binding of biotinylated-mAb 7C11 to rBla g 2-N93Q by mAb 7C11 epitope mutants.
Glesner, J., Wünschmann, S., Li, M., Gustchina, A., Wlodawer, A., Himly, M., ... & Pomés, A. (2011). Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding. PloS one, 6(7).
FuncS
Figure 3 Binding of IgE antibodies from cockroach allergic patients to rBla g 2-N93Q and epitope mutants.
IgE binding to mAb7C11 epitope mutants.
Glesner, J., Wünschmann, S., Li, M., Gustchina, A., Wlodawer, A., Himly, M., ... & Pomés, A. (2011). Mechanisms of allergen-antibody interaction of cockroach allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding. PloS one, 6(7).
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- IgG
- Specificity
- Tested positive against native B. germanica Aspartic protease Bla g 2
- Species Reactivity
- B. germanica
- Clone
- 7C11
- Applications
- ELISA, Inhib, FuncS
Product Property
- Purity
- >95% by SDS-PAGE and HPLC analysis
- Storage
- Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay, Inhibition and Function Assay.
Target
- Alternative Names
- Aspartic protease Bla g 2; Allergen Bla g II; Allergen: Bla g 2
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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ScFv Antibody Products
Fab Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-016 | Recombinant Mouse Anti-Aspartic protease Bla g 2 Antibody scFv Fragment (7C11) | WB, ELISA, IF, FuncS | scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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