Hi-Affi™ Rabbit Anti-CACNA1A Recombinant Antibody (clone DS430AB) (CAT#: MOR-0430)
Recombinant Rabbit anti-CACNA1A monoclonal antibody for WB, FC, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71902/1436_E6_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71902/1436_E6_3_selected.jpg
Figure 2 IHC staining of human cerebellum
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71902/168689_B_8_8_selected.jpg
(Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71902/168689_B_8_8_selected.jpg
Figure 3 High expression in cerebellum
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68138/168693_B_8_8_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68138/168693_B_8_8_selected.jpg
Figure 4 Low expression in liver
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68138/168693_A_7_4_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/68138/168693_A_7_4_val_selected.jpg
Figure 5 RNA cell line category: Group enriched (SCLC-21H, U-87 MG)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141837-CACNA1A
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000141837-CACNA1A
Specifications
- Immunogen
- Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CACNA1A aa 2050-2150 (Cysteine residue). The exact sequence is proprietary.
- Host Species
- Rabbit
- Derivation
- Phage display library screening
- Type
- Rabbit IgG
- Species Reactivity
- Mouse, Rat, Human
- Clone
- DS430AB
- Applications
- WB, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by analysis by SDS-PAGE
- Format
- Liquid
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Calcium Channel, Voltage-Dependent, P/Q Type, Alpha 1A Subunit; Voltage-Gated Calcium Channel Subunit Alpha Cav2.1; Brain Calcium Channel I; CACNL1A4; BI; Fetal Brain Ca2+ Voltage-Gated Channel Alpha1A Pore-Forming Subunit; Calcium Channel, L Type, Alpha-1 Polypeptide Isoform 4; Calcium Channel, L Type, Alpha-1 Polypeptide; Brain Calcium Channel 1; CAV2.1; CACH4; CACN3; APCA; HPCA; MHP1; SCA6; EA2; FHM; MHP
- Gene ID
- 773
- UniProt ID
- O00555
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2087z | Mouse Anti-CACNA1A Recombinant Antibody (clone 27B6) | WB, ELISA, IF, IP | Mouse IgG1, κ |
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