Recombinant Mouse anti-Human EWSR1 Monoclonal antibody (EML109)
CAT#: MOB-0616CT
Recombinant Mouse monoclonal antibody to Human EWSR1, expressed in Chinese Hamster Ovary cells(CHO).
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/51771/769_A1_3_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4230/if_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear Peripheral nerve/ganglion Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62953/142641_A_9_3.jpg
Normal Tissue
Figure 4 Liver
Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear Hepatocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62953/142641_A_7_4.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Nuclear Cells in tubules Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62953/142641_A_8_5.jpg
Normal Tissue
Figure 6 Testis
Leydig cells Staining: High Intensity: Strong Quantity:>75% Pachytene spermatocytes Staining: High Intensity: Strong Quantity:>75% Peritubular cells Staining: High Intensity: Strong Quantity:>75% Preleptotene spermatocytes Staining: High Intensity: Strong Quantity:>75% Round or early spermatids Staining: High Intensity: Strong Quantity:>75% Sertoli cells Staining: High Intensity: Strong Quantity:>75% Spermatogonia cells Staining: High Intensity: Strong
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62953/142641_A_6_6.jpg
Normal Tissue
Figure 7 Skin
Epidermal cells Staining: High Intensity: Strong Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62953/142641_B_6_8.jpg
Normal Tissue
Figure 8 Lymph node
Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/62953/142641_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000182944-EWSR1
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Specifications
- Immunogen
- Recombinant fragment: SDNSAIYVQG LNDSVTLDDL ADFFKQCGVV KMNKRTGQPM IHIYLDKETG KPKGDATVSY EDPPTAKAAV EWFDGKDFQG SKLKVSLARK KPPMNS, corresponding to amino acids 358-454 of Human EWSR1
- Host Species
- Mouse
- Species Reactivity
- Human
- Clone
- EML109
- Applications
- Used for immunoassay techniques such as: Immunohistochemistry paraffin embedded sections; Immunoprecipitation; Western Blot
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.0 mg/ml
- Buffer
- Preservative: None PBS, pH 7.2
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- EWSR1; EWS RNA-binding protein 1; EWS; bK984G1.4; RNA-binding protein EWS; EWS RNA-binding protein variant 6; Ewing sarcoma breakpoint region 1; Ewings sarcoma EWS-Fli1 (type 1) oncogene;
- Gene ID
- 2130
- UniProt ID
- Q01844
- Protein Refseq
- NP_001156757
- Function
- RNA binding; calmodulin binding; metal ion binding; nucleic acid binding; nucleotide binding; protein binding; zinc ion binding;
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-4064z | Mouse Anti-EWSR1 Recombinant Antibody (clone 31G5) | WB, ICC, IF, IHC | Mouse IgG2b, κ |
| VS3-WK387 | Rabbit Anti-EWSR1 Recombinant Antibody (clone JE49-57) | WB, ICC, IHC | Rabbit IgG |
| VS3-FY525 | Recombinant Rabbit Anti-EWSR1 Antibody (clone R09-3A7) | WB, ICC, IF | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| BRD-0198MZ | Chicken Anti-EWSR1 Polyclonal IgY | WB | Chicken antibody |
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| MOR-1212 | Hi-Affi™ Rabbit Anti-EWSR1 Recombinant Antibody (clone YC046) | WB, IHC, ICC | Rabbit IgG |
| CAT | Product Name | Application | Type |
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| VS-0724-YC447 | AbPlus™ Anti-EWSR1 Magnetic Beads (VS-0724-YC447) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
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| VS-0325-XY792 | Anti-EWSR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2380 | Anti-Mouse EWSR1 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2379 | Anti-Human EWSR1 Immunohistochemistry Kit | IHC |
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