Recombinant monoclonal antibody to insulin-like growth factor 1 receptor. IR3 is a human antibody that can be potentially used in the treatment of breast cancer.
Figure 1 Western blots were performed for p-Tyr1131 IGF-1R and total IGF-1R; actin was probed as loading control.
Experiments were repeated 3 times; representative blots are shown. Quantification (shown beneath each band) was normalized to actin and performed using Odyssey Li-Cor imaging software.
LeRoith, D., & Helman, L. (2004). The new kid on the block (ade) of the IGF-1 receptor. Cancer cell, 5(3), 201-202.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
NABL-091 | Recombinant Anti-human IGF1R VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
TAB-096ZJ | Anti-Human IGF-1R Therapeutic Single Domain Antibody (IGF1 R-3) | ELISA, IHC, IF, WB | Single domain antibody |
HPAB-1545-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (m632) | WB, ELISA | Llama VHH |
HPAB-1546-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (m636) | WB, ELISA | Llama VHH |
HPAB-1547-FY | Recombinant Llama Anti-IGF1R Single Domain Antibody (m546) | WB, ELISA | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L024E | IGF1-PE immunotoxin | Cytotoxicity assay, Functional assay | |
AGTO-L024D | IGF1-DT immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-386CL | Humanized Anti-IGF1R Recombinant Antibody (TAB-386CL) | FuncS | Humanized IgG |
TAB-035ZJ-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-035ZJ-F(E)) | ELISA, FC | Humanized Fab |
TAB-036ZJ-F(E) | Anti-Human IGF-1R Recombinant Antibody Fab Fragment (H0L0 IgGIm(AA)) | ELISA, Neut, FC, IHC | Humanized antibody |
TAB-037ZJ-F(E) | Anti-Human IGF-1R Recombinant Antibody Fab Fragment (H1L0 IgGIm(AA)) | ELISA, Neut, FC, IHC | Humanized antibody |
TAB-038ZJ-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-038ZJ-F(E)) | ELISA, FC, Inhib, IP | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-371CL | Afuco™ Anti-Human IGF1R Antibody, ADCC Enhanced (AFC-371CL) | ELISA | ADCC enhanced antibody |
AFC-TAB-199 | Afuco™ Anti-IGF1R Recombinant Antibody (AFC-TAB-199), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | Human IgG1, κ |
AFC-TAB-209 | Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Robatumumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
AFC-TAB-736 | Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Dalotuzumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
AFC-TAB-078 | Afuco™ Anti-IGF1R ADCC Recombinant Antibody (Cixutumumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-009ZJ | Mouse Anti-IGF1R Recombinant Antibody (TAB-009ZJ) | ELISA, FC | Mouse IgG1, κ |
TAB-010ZJ | Anti-Human IGF-1R Recombinant Antibody (6E11) | ELISA, Neut, FC, IHC | |
TAB-011ZJ | Mouse Anti-IGF1R Recombinant Antibody (TAB-011ZJ) | ELISA, FC, WB, Inhib | Mouse IgG2, κ |
TAB-012ZJ | Mouse Anti-IGF1R Recombinant Antibody (TAB-012ZJ) | ELISA, FC, WB, Inhib | Mouse IgG2, κ |
TAB-016ZJ-F(E) | Anti-Human IGF-1R Recombinant Antibody Fab Fragment (7C2) | IP, IHC, ELISA, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-084ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-084ZJ) | WB, Inhib, ELISA, FC | Chimeric (mouse/human) IgG |
TAB-085ZJ | Anti-Human IGF-1R Recombinant Antibody (6E11c) | ELISA, FC, IHC, Inhib | Chimeric antibody (mouse/human) |
TAB-086ZJ | Human Anti-IGF1R Recombinant Antibody (TAB-086ZJ) | ELISA, FC, Inhib, IP | Chimeric (mouse/human) IgG1 |
TAB-087ZJ | Anti-Human IGF-1R Recombinant Antibody (ch7C2) | ELISA | Chimeric antibody (mouse/human) |
TAB-093ZJ | Anti-Human IGF-1R Recombinant Antibody (ch9E11) | ELISA | Chimeric antibody (mouse/human) |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-052ZJ-S(P) | Anti-Human IGF-1R Recombinant Antibody scFv Fragment (18) | ELISA, FC, IF, IP | Human antibody |
TAB-055ZJ-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-055ZJ-F(E)) | ELISA | Human Fab |
TAB-056ZJ-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-056ZJ-F(E)) | ELISA | Human Fab |
TAB-057ZJ-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (TAB-057ZJ-F(E)) | ELISA | Human Fab |
TAB-058ZJ-F(E) | Anti-Human IGF-1R Recombinant Antibody Fab Fragment (1A) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0103MZ | Chicken Anti-CD221 Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1075CQ | Mouse Anti-IGF1R Recombinant Antibody (clone alphaIR3) | FC, IP, Neut, ICC, IF | Mouse IgG1 |
NEUT-1076CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 33255.111) | ELISA, Neut, WB | Mouse IgG1 |
NEUT-1081CQ | Mouse Anti-IGF1R Recombinant Antibody (clone CBL453) | WB, ELISA, Neut | Mouse IgG1 |
NEUT-1082CQ | Mouse Anti-IGF1R Recombinant Antibody (clone CBL080) | Neut, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1077CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 1H7) | FC, Block, IHC, IP, WB | Mouse IgG1, κ |
NEUT-1078CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 24-60) | Inhib, ICC, IF, IP, WB | Mouse IgG2a, κ |
NEUT-1079CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 17-69) | Inhib, IP | Mouse IgG1 |
NEUT-1080CQ | Mouse Anti-IGF1R Recombinant Antibody (clone 24-57) | Inhib, IP | Mouse IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1755 | Rabbit Anti-IGF1R Recombinant Antibody (clone DS1755AB) | IP, ELISA | Rabbit IgG |
MOR-4684 | Rabbit Anti-IGF1R Recombinant Antibody (clone TH198DS) | WB, ELISA | Rabbit IgG |
MOR-4685 | Rabbit Anti-IGF1R Recombinant Antibody (clone TH199DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-055CQ | Mouse Anti-IGF1R Recombinant Antibody (clone YC119) | WB, IP, IHC-P | Mouse IgG2a |
TAB-478CQ | Human Anti-IGF1R Recombinant Antibody (clone DalotuzumAb) | ELISA, IHC, FC, IP, IF, WB | Humanized IgG1, κ |
HPAB-1204-FY | Mouse Anti-IGF1R Recombinant Antibody (clone 2C6) | WB, FC, Inhib, FuncS | Mouse IgG1, κ |
HPAB-1205-FY | Mouse Anti-IGF1R Recombinant Antibody (clone 9H2) | WB | Mouse IgG1, κ |
HPAB-1206-FY | Mouse Anti-IGF1R Recombinant Antibody (clone 6E11) | ELISA, Inhib, WB | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-041CN | Mouse Anti-IGF1R Recombinant Antibody (NS-041CN) | ELISA, WB, FC | Mouse IgG |
NS-041CN-F(E) | Mouse Anti-IGF1R Recombinant Antibody; Fab Fragment (NS-041CN-F(E)) | ELISA, WB, FC | Mouse Fab |
NS-041CN-S(P) | Mouse Anti-IGF1R Recombinant Antibody; scFv Fragment (NS-041CN-S(P)) | ELISA, WB, FC | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0210CQ-F(E) | Human Anti-IGF1R Recombinant Antibody (clone 15H12); Fab Fragment | ELISA, FC, Neut | Human Fab |
HPAB-0211CQ-F(E) | Human Anti-IGF1R Recombinant Antibody (clone 1H3); Fab Fragment | ELISA, FC, Neut | Human Fab |
HPAB-0212CQ-F(E) | Human Anti-IGF1R Recombinant Antibody (clone 11A4); Fab Fragment | ELISA, FC, Block | Human Fab |
HPAB-0213CQ-F(E) | Human Anti-IGF1R Recombinant Antibody (clone 8A1); Fab Fragment | ELISA, FC, Block | Human Fab |
HPAB-0214CQ-F(E) | Human Anti-IGF1R Recombinant Antibody (clone PINT-9A2); Fab Fragment | ELISA, FC, Block | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1213-FY-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-1213-FY-F(E)) | ELISA | Human Fab |
HPAB-1214-FY-F(E) | Mouse Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-1214-FY-F(E)) | ELISA | Mouse Fab |
HPAB-1216-FY-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-1216-FY-F(E)) | ELISA | Human Fab |
HPAB-1732-FY-F(E) | Human Anti-IGF1R Recombinant Antibody; Fab Fragment (HPAB-1732-FY-F(E)) | WB, ELISA | Human Fab |
HPAB-1945-FY-S(P) | Human Anti-IGF1R Recombinant Antibody; scFv Fragment (HPAB-1945-FY-S(P)) | Inhib | Human scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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